Two sample MR report
FHAD1_Macrophages against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | 0.0258785 | 0.0541245 | 0.6471297 |
| Weighted median | 9 | -0.0165492 | 0.0073129 | 0.0236346 |
| Inverse variance weighted | 9 | -0.0169342 | 0.0058240 | 0.0036416 |
| Simple mode | 9 | -0.0158660 | 0.0117208 | 0.2128443 |
| Weighted mode | 9 | -0.0157075 | 0.0117716 | 0.2188182 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.527743 | 7 | 0.3760699 |
| Inverse variance weighted | 8.208866 | 8 | 0.4133381 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0305217 | 0.0383512 | 0.4522603 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003451 | 0 | TRUE | 0.0778356 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
