Two sample MR report
GABPB1-AS1_Epithelial against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.1242060 | 0.3745801 | 0.7717232 |
| Weighted median | 4 | 0.0749134 | 0.0391420 | 0.0556347 |
| Inverse variance weighted | 4 | 0.0694696 | 0.0348782 | 0.0463954 |
| Simple mode | 4 | 0.0817148 | 0.0539942 | 0.2273920 |
| Weighted mode | 4 | 0.0827718 | 0.0547040 | 0.2274666 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.040028 | 2 | 0.9801850 |
| Inverse variance weighted | 0.309704 | 3 | 0.9581932 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0953053 | 0.1835252 | 0.6553016 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001364 | 0 | TRUE | 0.267171 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
