Two sample MR report
GBP3_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 23 | 0.0548422 | 0.0361951 | 0.1446342 |
| Weighted median | 23 | 0.0240515 | 0.0083716 | 0.0040661 |
| Inverse variance weighted | 23 | 0.0148463 | 0.0062596 | 0.0177026 |
| Simple mode | 23 | 0.0268085 | 0.0127340 | 0.0469111 |
| Weighted mode | 23 | 0.0271695 | 0.0120299 | 0.0341687 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 17.93560 | 21 | 0.6530762 |
| Inverse variance weighted | 19.19428 | 22 | 0.6333025 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0270573 | 0.0241172 | 0.2745645 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0009932 | 0 | TRUE | 0.0027197 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
