Two sample MR report
GSTA1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | -0.0843306 | 0.1680012 | 0.6370112 |
| Weighted median | 7 | -0.0406249 | 0.0181015 | 0.0248145 |
| Inverse variance weighted | 7 | -0.0385104 | 0.0154888 | 0.0129068 |
| Simple mode | 7 | -0.0416353 | 0.0254379 | 0.1527989 |
| Weighted mode | 7 | -0.0415347 | 0.0253437 | 0.1523547 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.3697306 | 5 | 0.9961225 |
| Inverse variance weighted | 0.4447542 | 6 | 0.9984473 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0261166 | 0.0953493 | 0.7951132 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005418 | 0 | TRUE | 0.0267058 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
