Two sample MR report
GSTP1_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 19 | 0.0198099 | 0.0900296 | 0.8284625 |
| Weighted median | 19 | -0.0302877 | 0.0115637 | 0.0088139 |
| Inverse variance weighted | 19 | -0.0319863 | 0.0089831 | 0.0003698 |
| Simple mode | 19 | -0.0306313 | 0.0203802 | 0.1501825 |
| Weighted mode | 19 | -0.0290190 | 0.0194029 | 0.1520848 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.733994 | 17 | 0.9996764 |
| Inverse variance weighted | 4.068320 | 18 | 0.9997317 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.015999 | 0.0276699 | 0.5707036 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004204 | 0 | TRUE | 0.0512197 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
