Two sample MR report
GSTP1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 20 | -0.0855039 | 0.1694146 | 0.6198910 |
| Weighted median | 20 | 0.0501863 | 0.0214248 | 0.0191583 |
| Inverse variance weighted | 20 | 0.0527940 | 0.0158329 | 0.0008547 |
| Simple mode | 20 | 0.0698205 | 0.0378603 | 0.0808112 |
| Weighted mode | 20 | 0.0739778 | 0.0353386 | 0.0499626 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.444134 | 18 | 0.9485496 |
| Inverse variance weighted | 10.116396 | 19 | 0.9500158 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0424088 | 0.0517233 | 0.4229887 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004343 | 0 | TRUE | 0.0477054 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
