Two sample MR report
ITGB3BP_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.0001412 | 0.0619658 | 0.9983247 |
| Weighted median | 5 | -0.0308444 | 0.0170504 | 0.0704500 |
| Inverse variance weighted | 5 | -0.0346232 | 0.0144558 | 0.0166155 |
| Simple mode | 5 | -0.0317828 | 0.0221754 | 0.2250779 |
| Weighted mode | 5 | -0.0298194 | 0.0190408 | 0.1923895 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.4237681 | 3 | 0.935290 |
| Inverse variance weighted | 0.7512467 | 4 | 0.944862 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0240961 | 0.0421072 | 0.6072191 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002026 | 0 | TRUE | 0.176036 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
