Two sample MR report
KANSL1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.2162414 | 2.9127080 | 0.9528235 |
| Weighted median | 3 | 0.6267050 | 0.3310737 | 0.0583650 |
| Inverse variance weighted | 3 | 0.6290853 | 0.2838637 | 0.0266810 |
| Simple mode | 3 | 0.6377096 | 0.4037891 | 0.2550268 |
| Weighted mode | 3 | 0.6158845 | 0.3866719 | 0.2522193 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0000508 | 1 | 0.9943140 |
| Inverse variance weighted | 0.0203333 | 2 | 0.9898848 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.2282697 | 1.602828 | 0.9099403 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.13e-05 | 0 | TRUE | 0.6621405 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
