Two sample MR report
LDLRAD1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | 0.0501369 | 0.1423532 | 0.7350529 |
| Weighted median | 9 | 0.0257992 | 0.0160628 | 0.1082410 |
| Inverse variance weighted | 9 | 0.0292512 | 0.0135340 | 0.0306711 |
| Simple mode | 9 | 0.0289619 | 0.0253848 | 0.2869052 |
| Weighted mode | 9 | 0.0293739 | 0.0217529 | 0.2138611 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.817933 | 7 | 0.8004930 |
| Inverse variance weighted | 3.839655 | 8 | 0.8712927 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0088133 | 0.0597981 | 0.8869835 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001486 | 0 | TRUE | 0.2468089 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
