Two sample MR report
LKAAEAR1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 17 | -0.0242783 | 0.0411554 | 0.5640271 |
| Weighted median | 17 | 0.0329801 | 0.0066109 | 0.0000006 |
| Inverse variance weighted | 17 | 0.0347897 | 0.0053301 | 0.0000000 |
| Simple mode | 17 | 0.0344320 | 0.0099559 | 0.0032353 |
| Weighted mode | 17 | 0.0289449 | 0.0090503 | 0.0055986 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 17.79610 | 15 | 0.2735367 |
| Inverse variance weighted | 20.27899 | 16 | 0.2079169 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0536923 | 0.037115 | 0.1685695 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0011684 | 1e-07 | TRUE | 0.0012032 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
