Two sample MR report
LRRC46_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | 0.1752526 | 0.1512267 | 0.2845091 |
| Weighted median | 9 | 0.0228380 | 0.0197554 | 0.2476648 |
| Inverse variance weighted | 9 | 0.0393484 | 0.0154155 | 0.0106946 |
| Simple mode | 9 | 0.0198902 | 0.0248513 | 0.4466119 |
| Weighted mode | 9 | 0.0203808 | 0.0226121 | 0.3937402 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 6.389416 | 7 | 0.4950843 |
| Inverse variance weighted | 7.205520 | 8 | 0.5146299 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0640589 | 0.0709098 | 0.3963443 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001397 | 0 | TRUE | 0.2632388 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
