Two sample MR report
MARVELD1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 31 | 0.0386107 | 0.0336615 | 0.2607463 |
| Weighted median | 31 | -0.0195352 | 0.0047989 | 0.0000469 |
| Inverse variance weighted | 31 | -0.0176163 | 0.0036356 | 0.0000013 |
| Simple mode | 31 | -0.0251708 | 0.0095395 | 0.0130723 |
| Weighted mode | 31 | -0.0235677 | 0.0091696 | 0.0153717 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.663635 | 29 | 0.9999754 |
| Inverse variance weighted | 10.486675 | 30 | 0.9996306 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.049013 | 0.0291711 | 0.1036629 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0007371 | 0 | TRUE | 0.0098922 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
