Two sample MR report
MRI1_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0101658 | 0.1414351 | 0.9543208 |
| Weighted median | 3 | 0.0303834 | 0.0142663 | 0.0331938 |
| Inverse variance weighted | 3 | 0.0280276 | 0.0117210 | 0.0167917 |
| Simple mode | 3 | 0.0351496 | 0.0163464 | 0.1645012 |
| Weighted mode | 3 | 0.0339803 | 0.0173472 | 0.1892221 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.7953725 | 1 | 0.3724805 |
| Inverse variance weighted | 0.8114319 | 2 | 0.6664995 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0106623 | 0.084137 | 0.9197515 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.14e-05 | 0 | TRUE | 0.5425915 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
