Two sample MR report
MRI1_Epithelial against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0394310 | 0.3721124 | 0.9327912 |
| Weighted median | 3 | -0.0804595 | 0.0381390 | 0.0348894 |
| Inverse variance weighted | 3 | -0.0946263 | 0.0309341 | 0.0022210 |
| Simple mode | 3 | -0.0761054 | 0.0447550 | 0.2311428 |
| Weighted mode | 3 | -0.0740247 | 0.0472663 | 0.2578156 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.907412 | 1 | 0.3408020 |
| Inverse variance weighted | 1.038102 | 2 | 0.5950849 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.080022 | 0.221354 | 0.779161 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.14e-05 | 0 | TRUE | 0.544214 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
