Two sample MR report
MTG2_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0598505 | 0.5039525 | 0.9247461 |
| Weighted median | 3 | 0.0243805 | 0.0124673 | 0.0505165 |
| Inverse variance weighted | 3 | 0.0236668 | 0.0103923 | 0.0227651 |
| Simple mode | 3 | 0.0261200 | 0.0142743 | 0.2087627 |
| Weighted mode | 3 | 0.0261962 | 0.0154511 | 0.2320811 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.2178477 | 1 | 0.6406848 |
| Inverse variance weighted | 0.2453240 | 2 | 0.8845626 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0564662 | 0.3406508 | 0.8954248 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.44e-05 | 0 | TRUE | 0.5275606 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
