Two sample MR report
NAGK_Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 15 | -0.0942196 | 0.0786579 | 0.2523635 |
| Weighted median | 15 | -0.0453420 | 0.0134899 | 0.0007761 |
| Inverse variance weighted | 15 | -0.0262387 | 0.0108357 | 0.0154566 |
| Simple mode | 15 | -0.0556833 | 0.0259641 | 0.0500147 |
| Weighted mode | 15 | -0.0542325 | 0.0223709 | 0.0294669 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 17.17500 | 13 | 0.1914273 |
| Inverse variance weighted | 18.18125 | 14 | 0.1986500 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0387694 | 0.0444234 | 0.3986466 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002861 | 0 | TRUE | 0.1086752 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
