Two sample MR report
NAPRT_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | 0.0334486 | 0.0222815 | 0.1675510 |
| Weighted median | 11 | 0.0108004 | 0.0073757 | 0.1431066 |
| Inverse variance weighted | 11 | 0.0130287 | 0.0059739 | 0.0291886 |
| Simple mode | 11 | 0.0094285 | 0.0117517 | 0.4410268 |
| Weighted mode | 11 | 0.0081466 | 0.0114097 | 0.4915484 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.526830 | 9 | 0.9801532 |
| Inverse variance weighted | 3.431759 | 10 | 0.9693648 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0164511 | 0.0172937 | 0.3663097 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002417 | 0 | TRUE | 0.1396962 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
