Two sample MR report
NOXA1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0689443 | 0.6615856 | 0.9338960 |
| Weighted median | 3 | -0.0529977 | 0.0193349 | 0.0061244 |
| Inverse variance weighted | 3 | -0.0537386 | 0.0157202 | 0.0006298 |
| Simple mode | 3 | -0.0527460 | 0.0219629 | 0.1383030 |
| Weighted mode | 3 | -0.0527171 | 0.0208250 | 0.1269957 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0088840 | 1 | 0.9249065 |
| Inverse variance weighted | 0.0094126 | 2 | 0.9953048 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0099954 | 0.4347686 | 0.9853665 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.12e-05 | 0 | TRUE | 0.5463049 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
