Two sample MR report
NUDT2_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.0178238 | 0.0665295 | 0.7964932 |
| Weighted median | 9 | -0.0308980 | 0.0178135 | 0.0828254 |
| Inverse variance weighted | 9 | -0.0329015 | 0.0128998 | 0.0107558 |
| Simple mode | 9 | -0.0667616 | 0.0237003 | 0.0226012 |
| Weighted mode | 9 | -0.0199321 | 0.0193896 | 0.3340347 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 5.706243 | 7 | 0.5744375 |
| Inverse variance weighted | 5.759612 | 8 | 0.6741384 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0090788 | 0.0392993 | 0.8239093 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001786 | 0 | TRUE | 0.2049216 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
