Two sample MR report
NUTM2B-AS1_Epithelial against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.1120350 | 1.0693525 | 0.9335444 |
| Weighted median | 3 | -0.0992157 | 0.0484658 | 0.0406456 |
| Inverse variance weighted | 3 | -0.0998863 | 0.0410234 | 0.0148975 |
| Simple mode | 3 | -0.1098119 | 0.0531392 | 0.1747480 |
| Weighted mode | 3 | -0.0921657 | 0.0557239 | 0.2399549 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0686262 | 1 | 0.7933477 |
| Inverse variance weighted | 0.1079582 | 2 | 0.9474519 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1375769 | 0.6937004 | 0.8753609 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.03e-05 | 0 | TRUE | 0.5478884 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
