Two sample MR report
PARK7_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 21 | 0.0283780 | 0.0474534 | 0.5568895 |
| Weighted median | 21 | -0.0401671 | 0.0167761 | 0.0166521 |
| Inverse variance weighted | 21 | -0.0597382 | 0.0121682 | 0.0000009 |
| Simple mode | 21 | -0.0536467 | 0.0256549 | 0.0494911 |
| Weighted mode | 21 | -0.0423219 | 0.0221852 | 0.0708977 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.700795 | 19 | 0.9599444 |
| Inverse variance weighted | 13.391547 | 20 | 0.8599597 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0337972 | 0.0175923 | 0.0698475 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002888 | 0 | TRUE | 0.107923 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
