Two sample MR report
PIGP_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.0366790 | 0.1529471 | 0.8222619 |
| Weighted median | 6 | -0.0528184 | 0.0185639 | 0.0044381 |
| Inverse variance weighted | 6 | -0.0541256 | 0.0147640 | 0.0002463 |
| Simple mode | 6 | -0.0562616 | 0.0252983 | 0.0767481 |
| Weighted mode | 6 | -0.0544942 | 0.0263104 | 0.0930974 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.5581236 | 4 | 0.9676015 |
| Inverse variance weighted | 0.9139180 | 5 | 0.9692059 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0410944 | 0.0688942 | 0.582969 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.96e-05 | 0 | TRUE | 0.4656891 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
