Two sample MR report
PLA2G16_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.0123818 | 0.1339522 | 0.9321798 |
| Weighted median | 5 | -0.0567183 | 0.0200843 | 0.0047426 |
| Inverse variance weighted | 5 | -0.0612033 | 0.0159559 | 0.0001252 |
| Simple mode | 5 | -0.0558812 | 0.0248807 | 0.0880378 |
| Weighted mode | 5 | -0.0560213 | 0.0241041 | 0.0807690 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1769159 | 3 | 0.9812269 |
| Inverse variance weighted | 0.3116658 | 4 | 0.9890487 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0241158 | 0.0656957 | 0.7379224 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.11e-05 | 0 | TRUE | 0.4609196 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
