Two sample MR report
PLOD2_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.2282608 | 0.2072915 | 0.3072452 |
| Weighted median | 9 | -0.0277253 | 0.0174528 | 0.1121548 |
| Inverse variance weighted | 9 | -0.0495894 | 0.0136803 | 0.0002891 |
| Simple mode | 9 | -0.0890585 | 0.0348292 | 0.0338040 |
| Weighted mode | 9 | -0.0131934 | 0.0242631 | 0.6014249 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 10.89586 | 7 | 0.1432267 |
| Inverse variance weighted | 12.05749 | 8 | 0.1486573 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0966498 | 0.111879 | 0.4162715 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002026 | 0 | TRUE | 0.1795716 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
