Two sample MR report
RRP7A_Epithelial against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 16 | 0.0771671 | 0.1105873 | 0.4967332 |
| Weighted median | 16 | -0.0770389 | 0.0181602 | 0.0000221 |
| Inverse variance weighted | 16 | -0.0597255 | 0.0173880 | 0.0005928 |
| Simple mode | 16 | -0.0905640 | 0.0272459 | 0.0046260 |
| Weighted mode | 16 | -0.0815285 | 0.0276220 | 0.0099017 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 22.86869 | 14 | 0.0624402 |
| Inverse variance weighted | 25.43277 | 15 | 0.0444248 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1018342 | 0.0812802 | 0.2307729 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002056 | 0 | TRUE | 0.1757197 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
