Two sample MR report
RRP7A_Macrophages against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 16 | -0.0500250 | 0.0863790 | 0.5717005 |
| Weighted median | 16 | -0.0806094 | 0.0176364 | 0.0000049 |
| Inverse variance weighted | 16 | -0.0619951 | 0.0161890 | 0.0001284 |
| Simple mode | 16 | -0.0818786 | 0.0239318 | 0.0037882 |
| Weighted mode | 16 | -0.0818786 | 0.0239184 | 0.0037734 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 23.04894 | 14 | 0.0594780 |
| Inverse variance weighted | 23.08179 | 15 | 0.0824186 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.009166 | 0.0648891 | 0.8896802 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005935 | 0 | TRUE | 0.0208859 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
