Two sample MR report
S100A13_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | -0.0245588 | 0.0741180 | 0.7479669 |
| Weighted median | 11 | -0.0301784 | 0.0090043 | 0.0008036 |
| Inverse variance weighted | 11 | -0.0300419 | 0.0072349 | 0.0000329 |
| Simple mode | 11 | -0.0303373 | 0.0134125 | 0.0472189 |
| Weighted mode | 11 | -0.0303373 | 0.0131190 | 0.0433255 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.8910125 | 9 | 0.9996503 |
| Inverse variance weighted | 0.8965378 | 10 | 0.9998960 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.002701 | 0.0363372 | 0.9423716 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002298 | 0 | TRUE | 0.150583 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
