Two sample MR report
SMDT1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | -0.0552236 | 0.0793904 | 0.5011134 |
| Weighted median | 13 | 0.0218717 | 0.0177027 | 0.2166455 |
| Inverse variance weighted | 13 | 0.0267059 | 0.0132292 | 0.0435170 |
| Simple mode | 13 | 0.0154074 | 0.0258431 | 0.5621264 |
| Weighted mode | 13 | 0.0327158 | 0.0245374 | 0.2071910 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.048183 | 11 | 0.9900737 |
| Inverse variance weighted | 4.143589 | 12 | 0.9807037 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0360454 | 0.0344399 | 0.31773 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005714 | 0 | TRUE | 0.0229562 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
