Two sample MR report
SNHG8_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | 0.0327281 | 0.0487900 | 0.5191933 |
| Weighted median | 11 | -0.0297198 | 0.0106924 | 0.0054437 |
| Inverse variance weighted | 11 | -0.0294305 | 0.0082091 | 0.0003369 |
| Simple mode | 11 | -0.0284773 | 0.0175197 | 0.1351292 |
| Weighted mode | 11 | -0.0290574 | 0.0154552 | 0.0895091 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.903040 | 9 | 0.9176774 |
| Inverse variance weighted | 5.573409 | 10 | 0.8497408 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0290259 | 0.0224585 | 0.2284036 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002271 | 0 | TRUE | 0.1534308 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
