Two sample MR report
SNHG8_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 10 | 0.2131595 | 0.0980649 | 0.0614672 |
| Weighted median | 10 | 0.0252302 | 0.0190680 | 0.1857797 |
| Inverse variance weighted | 10 | 0.0337232 | 0.0144886 | 0.0199353 |
| Simple mode | 10 | 0.0163055 | 0.0311197 | 0.6129641 |
| Weighted mode | 10 | 0.0133689 | 0.0311446 | 0.6778324 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.177041 | 8 | 0.9750975 |
| Inverse variance weighted | 5.599818 | 9 | 0.7792052 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0776611 | 0.0419773 | 0.101465 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002203 | 0 | TRUE | 0.1588396 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
