Two sample MR report
SOD1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0290014 | 0.6535595 | 0.9717689 |
| Weighted median | 3 | 0.0440405 | 0.0222944 | 0.0482225 |
| Inverse variance weighted | 3 | 0.0454444 | 0.0180837 | 0.0119710 |
| Simple mode | 3 | 0.0429242 | 0.0255889 | 0.2354530 |
| Weighted mode | 3 | 0.0427567 | 0.0252609 | 0.2326072 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0400397 | 1 | 0.841403 |
| Inverse variance weighted | 0.0530247 | 2 | 0.973836 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0380874 | 0.3342415 | 0.9277676 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.56e-05 | 0 | TRUE | 0.6328099 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
