Two sample MR report
SULT1A1_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.2144453 | 0.2651908 | 0.5036191 |
| Weighted median | 4 | -0.0365380 | 0.0150412 | 0.0151326 |
| Inverse variance weighted | 4 | -0.0321987 | 0.0121225 | 0.0079047 |
| Simple mode | 4 | -0.0368697 | 0.0194741 | 0.1546541 |
| Weighted mode | 4 | -0.0368148 | 0.0189450 | 0.1472424 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0759288 | 2 | 0.9627472 |
| Inverse variance weighted | 0.5492000 | 3 | 0.9079568 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0931055 | 0.1353382 | 0.5625593 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.03e-05 | 0 | TRUE | 0.46207 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
