Two sample MR report
SULT2B1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.1448362 | 0.9054645 | 0.8876093 |
| Weighted median | 4 | -0.0697601 | 0.0208100 | 0.0008016 |
| Inverse variance weighted | 4 | -0.0698202 | 0.0170603 | 0.0000427 |
| Simple mode | 4 | -0.0660675 | 0.0271103 | 0.0927488 |
| Weighted mode | 4 | -0.0732096 | 0.0256200 | 0.0647085 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0591239 | 2 | 0.9708707 |
| Inverse variance weighted | 0.0659902 | 3 | 0.9955797 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0419046 | 0.5057106 | 0.9415075 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.63e-05 | 0 | TRUE | 0.4441959 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
