Two sample MR report
TBCA_Epithelial against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.3746324 | 1.4072239 | 0.8150027 |
| Weighted median | 4 | 0.1689485 | 0.0765372 | 0.0272858 |
| Inverse variance weighted | 4 | 0.1671786 | 0.0637253 | 0.0087050 |
| Simple mode | 4 | 0.1656143 | 0.0967395 | 0.1854251 |
| Weighted mode | 4 | 0.1651118 | 0.0862682 | 0.1515383 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1420337 | 2 | 0.9314462 |
| Inverse variance weighted | 0.2905797 | 3 | 0.9617903 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.2574818 | 0.6680611 | 0.7370591 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.02e-05 | 0 | TRUE | 0.4623526 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
