Two sample MR report
TFF3_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0038953 | 0.0975595 | 0.9717784 |
| Weighted median | 4 | -0.0343347 | 0.0146608 | 0.0191838 |
| Inverse variance weighted | 4 | -0.0306659 | 0.0122818 | 0.0125299 |
| Simple mode | 4 | -0.0359739 | 0.0193706 | 0.1602847 |
| Weighted mode | 4 | -0.0364064 | 0.0192598 | 0.1551125 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.3279558 | 2 | 0.8487608 |
| Inverse variance weighted | 0.4044655 | 3 | 0.9393185 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0142872 | 0.0516522 | 0.8080486 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.85e-05 | 0 | TRUE | 0.4327884 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
