Two sample MR report
TMEM80_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.1886391 | 0.2762831 | 0.5437480 |
| Weighted median | 5 | 0.0570601 | 0.0180980 | 0.0016169 |
| Inverse variance weighted | 5 | 0.0519597 | 0.0137199 | 0.0001524 |
| Simple mode | 5 | 0.0619832 | 0.0248470 | 0.0671537 |
| Weighted mode | 5 | 0.0599394 | 0.0243660 | 0.0696944 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.991879 | 3 | 0.5740939 |
| Inverse variance weighted | 2.237220 | 4 | 0.6922211 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0757027 | 0.1528362 | 0.6543842 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 7.46e-05 | 0 | TRUE | 0.4154397 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
