Two sample MR report
TOB1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.1222418 | 0.2505121 | 0.6404853 |
| Weighted median | 9 | -0.0357149 | 0.0161305 | 0.0268209 |
| Inverse variance weighted | 9 | -0.0295968 | 0.0125950 | 0.0187796 |
| Simple mode | 9 | -0.0406534 | 0.0238142 | 0.1261868 |
| Weighted mode | 9 | -0.0410811 | 0.0232524 | 0.1152561 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.479102 | 7 | 0.9830243 |
| Inverse variance weighted | 1.616217 | 8 | 0.9906058 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0405141 | 0.1094117 | 0.7221162 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 8.45e-05 | 0 | TRUE | 0.3827371 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
