Two sample MR report
TOX_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -2.6261093 | 5.5242966 | 0.7174976 |
| Weighted median | 3 | -0.0485101 | 0.0254313 | 0.0564566 |
| Inverse variance weighted | 3 | -0.0424441 | 0.0201551 | 0.0352151 |
| Simple mode | 3 | -0.0502497 | 0.0274797 | 0.2089653 |
| Weighted mode | 3 | -0.0502497 | 0.0282654 | 0.2174133 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0901804 | 1 | 0.7639479 |
| Inverse variance weighted | 0.3089184 | 2 | 0.8568784 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 1.302458 | 2.784849 | 0.7214975 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.98e-05 | 0 | TRUE | 0.6051512 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
