Two sample MR report
TTC32_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.1904649 | 0.2173907 | 0.4454480 |
| Weighted median | 5 | 0.0288815 | 0.0146364 | 0.0484658 |
| Inverse variance weighted | 5 | 0.0271135 | 0.0112590 | 0.0160328 |
| Simple mode | 5 | 0.0292726 | 0.0184432 | 0.1876632 |
| Weighted mode | 5 | 0.0291152 | 0.0184492 | 0.1896761 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.320453 | 3 | 0.7242820 |
| Inverse variance weighted | 1.886602 | 4 | 0.7566059 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1426047 | 0.189526 | 0.5064501 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 9.74e-05 | 0 | TRUE | 0.349129 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
