Two sample MR report
TTLL10_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.2056235 | 1.0876951 | 0.8810538 |
| Weighted median | 3 | -0.0720516 | 0.0233854 | 0.0020627 |
| Inverse variance weighted | 3 | -0.0721993 | 0.0188921 | 0.0001326 |
| Simple mode | 3 | -0.0738332 | 0.0284252 | 0.1217378 |
| Weighted mode | 3 | -0.0715700 | 0.0282700 | 0.1269779 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0256394 | 1 | 0.8727841 |
| Inverse variance weighted | 0.0909003 | 2 | 0.9555673 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1972434 | 0.7721047 | 0.8407733 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.76e-05 | 0 | TRUE | 0.5650857 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
