Two sample MR report
TUBGCP2_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.1575761 | 0.1530720 | 0.3614534 |
| Weighted median | 6 | 0.0531846 | 0.0222148 | 0.0166611 |
| Inverse variance weighted | 6 | 0.0409507 | 0.0167281 | 0.0143645 |
| Simple mode | 6 | 0.0584561 | 0.0301377 | 0.1101224 |
| Weighted mode | 6 | 0.0599389 | 0.0294218 | 0.0972120 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.147249 | 4 | 0.3864445 |
| Inverse variance weighted | 4.756653 | 5 | 0.4462945 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0785696 | 0.1024829 | 0.4860286 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.34e-05 | 0 | TRUE | 0.4509993 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
