Two sample MR report
UCHL3_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.0664000 | 0.1737688 | 0.7278365 |
| Weighted median | 5 | -0.0267638 | 0.0142689 | 0.0607002 |
| Inverse variance weighted | 5 | -0.0314975 | 0.0116856 | 0.0070302 |
| Simple mode | 5 | -0.0254830 | 0.0183350 | 0.2369256 |
| Weighted mode | 5 | -0.0254076 | 0.0174622 | 0.2193621 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.5541019 | 3 | 0.9068545 |
| Inverse variance weighted | 0.5946285 | 4 | 0.9636587 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0268553 | 0.1334014 | 0.8533312 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.91e-05 | 0 | TRUE | 0.4670071 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
