Two sample MR report
WBSCR27_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 15 | -0.0303023 | 0.0401143 | 0.4634774 |
| Weighted median | 15 | 0.0512832 | 0.0101605 | 0.0000004 |
| Inverse variance weighted | 15 | 0.0560956 | 0.0084203 | 0.0000000 |
| Simple mode | 15 | 0.0505982 | 0.0201463 | 0.0249047 |
| Weighted mode | 15 | 0.0457902 | 0.0176178 | 0.0210147 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 16.81387 | 13 | 0.2079531 |
| Inverse variance weighted | 23.02892 | 14 | 0.0598007 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0646311 | 0.0294837 | 0.0471769 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006252 | 3e-07 | TRUE | 0.0195131 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
