Two sample MR report
XBP1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 15 | -0.0774455 | 0.0604808 | 0.2227463 |
| Weighted median | 15 | -0.0244253 | 0.0148327 | 0.0996146 |
| Inverse variance weighted | 15 | -0.0232921 | 0.0106386 | 0.0285680 |
| Simple mode | 15 | -0.0017696 | 0.0312041 | 0.9555769 |
| Weighted mode | 15 | -0.0535225 | 0.0280361 | 0.0769677 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 15.02949 | 13 | 0.3055152 |
| Inverse variance weighted | 15.98633 | 14 | 0.3142096 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0254907 | 0.0280196 | 0.379516 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002204 | 0 | TRUE | 0.1591448 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
