Two sample MR report
ZNF880_Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0497868 | 0.2787991 | 0.8747226 |
| Weighted median | 4 | -0.0548977 | 0.0203796 | 0.0070650 |
| Inverse variance weighted | 4 | -0.0463051 | 0.0169140 | 0.0061874 |
| Simple mode | 4 | -0.0592598 | 0.0303323 | 0.1457476 |
| Weighted mode | 4 | -0.0584602 | 0.0283777 | 0.1314862 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.433809 | 2 | 0.4882614 |
| Inverse variance weighted | 1.433965 | 3 | 0.6975927 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0019148 | 0.1530473 | 0.9911537 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.36e-05 | 0 | TRUE | 0.4894291 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
