Two sample MR report
ZSWIM7_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 26 | 0.0931655 | 0.1233252 | 0.4573324 |
| Weighted median | 26 | -0.0356646 | 0.0130891 | 0.0064349 |
| Inverse variance weighted | 26 | -0.0355163 | 0.0096455 | 0.0002313 |
| Simple mode | 26 | -0.0383741 | 0.0220465 | 0.0940508 |
| Weighted mode | 26 | -0.0352220 | 0.0221234 | 0.1239348 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 11.48694 | 24 | 0.9850946 |
| Inverse variance weighted | 12.58239 | 25 | 0.9812204 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0662177 | 0.0632669 | 0.3056926 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005587 | 0 | TRUE | 0.0246988 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
