Two sample MR report
hemoglobin concentration (HGB) against Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium || id:finn-b-O15_OEDEM_PROTUR_HYPERT
Date: 24 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 34 | 0.6979027 | 0.3230592 | 0.0383451 |
| Weighted median | 34 | 0.6598272 | 0.2309766 | 0.0042809 |
| Inverse variance weighted | 34 | 0.5226597 | 0.1627734 | 0.0013229 |
| Simple mode | 34 | 0.3262198 | 0.4937588 | 0.5133995 |
| Weighted mode | 34 | 0.7166816 | 0.2244433 | 0.0030883 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 41.15035 | 32 | 0.1288974 |
| Inverse variance weighted | 41.66072 | 33 | 0.1433417 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0044958 | 0.0071363 | 0.533178 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6e-06 | 0 | TRUE | 0.5083192 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
