Two sample MR report
Polycystic ovary syndrome against Endometrial cancer || id:ebi-a-GCST006464
Date: 22 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | 0.137 | 0.272 | 0.630 |
| Weighted median | 9 | -0.028 | 0.068 | 0.682 |
| Inverse variance weighted | 9 | -0.040 | 0.049 | 0.406 |
| Simple mode | 9 | -0.023 | 0.104 | 0.827 |
| Weighted mode | 9 | -0.030 | 0.103 | 0.779 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.37 | 7 | 0.391 |
| Inverse variance weighted | 7.84 | 8 | 0.450 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.023 | 0.035 | 0.529 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.789 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
