Two sample MR report
Polycystic ovary syndrome against Endometrial cancer (endometrioid histology) || id:ebi-a-GCST006465
Date: 22 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.210 | 0.359 | 0.577 |
| Weighted median | 9 | -0.020 | 0.080 | 0.800 |
| Inverse variance weighted | 9 | -0.014 | 0.063 | 0.829 |
| Simple mode | 9 | 0.024 | 0.129 | 0.856 |
| Weighted mode | 9 | 0.010 | 0.126 | 0.938 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.02 | 7 | 0.251 |
| Inverse variance weighted | 9.42 | 8 | 0.308 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.025 | 0.045 | 0.595 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.84 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
