Two sample MR report
eqtl-a-ENSG00000133067 against phenotype
Date: 11 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.052 | 0.052 | 0.374 |
| Weighted median | 6 | 0.033 | 0.013 | 0.011 |
| Inverse variance weighted | 6 | 0.036 | 0.015 | 0.017 |
| Simple mode | 6 | 0.007 | 0.040 | 0.869 |
| Weighted mode | 6 | 0.032 | 0.013 | 0.063 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.04 | 4 | 0.134 |
| Inverse variance weighted | 7.22 | 5 | 0.204 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.006 | 0.018 | 0.759 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.001 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
